Less joint pain means more ease of movement, so it is vital to keep knee osteoarthritis pain under control.

Common over-the-counter analgesics and nonsteroidal anti-inflammatory medications are frequently used to alleviate joint pain and reduce inflammation, including:

  • acetaminophen
  • aspirin
  • ibuprofen
  • naproxen

Effective doses vary, and there are potential side effects with long-term use, including stomach bleeding, liver damage and increased risk of stroke. Some doctors may prescribe stronger painkillers such as opioids or a combination of painkillers to ensure optimal pain alleviation.