With its proven effectiveness, affordability, excellent safety profile, and flexible dosing options, SUPARTZ FX is chosen worldwide as a preferred hyaluronic acid treatment to manage knee osteoarthritis:39

  • 410 million injections and more than 30 years of use worldwide39
  • More than 20 prospective clinical trials in the published literature44
  • Demonstrated safe with repeat injection cycles42

SUPARTZ FX targets knee osteoarthritis in 3 ways

Middel 1
Mechanical
Middel 5
Cellular
Middel 3
Biochemical

SUPARTZ FX MECHANISM OF ACTION

In targeting mechanical and cellular levels in animal models and biochemical levels in cell cultures, SUPARTZ FX inhibits IL-1β, MMP-3, and NO pathways, leading to reduced pain and inflammatory reactions, and protects nociceptors, which also reduces osteoarthritis knee pain.

‡Evidence obtained in preclinical studies. The clinical relevance of this information has not been determined

 

SUPARTZ FX Mechanism of Action Video