Proven in more clinical studies than any other single-injection hyaluronic acid knee therapy, DUROLANE has been shown to be safe and effective.

During the DUROLANE pivotal trial:17

  • No serious adverse events were considered related to DUROLANE treatment.17
  • The most common adverse events were arthralgia (8.6%), injection site pain (2.3%), and joint swelling (1.7%).17

DUROLANE is safe for repeated courses of therapy. Repeat administration of a course of DUROLANE therapy does not increase the incidence of adverse events.10,17

Choose DUROLANE for Longer-lasting Results

  • Increased residence time in the knee joint ‡27,29-32
  • A half-life of 4 weeks in the knee joint, in both animals and humans.16,29
  • The longest reported half-life of any hyaluronic acid product.29-32

The clinical relevance of this information has not been determined.