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References
- Ågerup B, Berg P, Åkermark C. Non-animal stabilized hyaluronic acid: a new formulation for the treatment of osteoarthritis. BioDrugs. 2005;19(1):23-30. doi:10.2165/00063030-200519010-00003
- Leighton R, Åkermark C, Therrien R, et al. NASHA hyaluronic acid vs. methylprednisolone for knee osteoarthritis: a prospective, multi-centre, randomized, non-inferiority trial. Osteoarthritis Cartilage. 2014;22(1):17-25. doi:10.1016/j.joca.2013.10.009
- Arden NK, Åkermark C, Andersson M, Todman MG, Altman RD. A randomized saline-controlled trial of NASHA hyaluronic acid for knee osteoarthritis. Curr Med Res Opin. 2014;30(2):279-86. doi:10.1185/03007995.2013.855631
- McGrath AF, McGrath AM, Jessop ZM, et al. A comparison of intra-articular hyaluronic acid competitors in the treatment of mild to moderate knee osteoarthritis. J Arthritis. 2013;2(1):1000108. doi:10.4172/2167-7921.1000108
- Krocker D, Matziolis G, Tuischer J, et al. Reduction of arthrosis associated knee pain through a single intra-articular injection of synthetic hyaluronic acid. Z Rheumatol. 2006;65(4):327-31. doi:10.1007/s00393-006-0063-2
- Altman RD, Åkermark C, Beaulieu AD, Schnitzer T. Efficacy and safety of a single intra-articular injection of non-animal stabilized hyaluronic acid (NASHA) in patients with osteoarthritis of the knee. Osteoarthritis Cartilage. 2004;12(8):642-49. doi:10.1016/j.joca.2004.04.010
- Conrozier T, Couris CM, Mathieu P, et al. Safety, efficacy and predictive factors of efficacy of a single intra-articular injection of non-animal-stabilized-hyaluronic-acid in the hip joint: results of a standardized follow-up of patients treated for hip osteoarthritis in daily practice. Arch Orthop Trauma Surg. 2009;129(6):843-8. doi:10.1007/s00402-008-0778-4
- Berg P, Olsson U. Intra-articular injection of non-animal stabilised hyaluronic acid (NASHA) for osteoarthritis of the hip: A pilot study. Clin Exp Rheumatol. 2004;22(3):300-6.
- Altman R, Lim S, Steen RG, Dasa V. Hyaluronic acid injections are associated with delay of total knee replacement surgery in patients with knee osteoarthritis: evidence from a large U.S. health claims database. PLoS One. 2015;10(12):e0145776. doi:10.1371/journal.pone.0145776
- Romero Jurado M, Enrique Fidalgo A, Rodríguez Villar V, Mar Medina J, Soler López B. Factors related with the time to surgery in waiting-list patients for knee prostheses. Reumatol Clin. 2013;9(3):148-55. doi:10.1016/j.reuma.2012.09.003
- Kompel AJ, Roemer FW, Murakami AM, Diaz LE, Crema MD, Guermazi A. Intra-articular corticosteroid injections in the hip and knee: Perhaps not as safe as we thought? Radiology. 2019;293(3):656-63. doi:10.1148/radiol.2019190341
- McAlindon TE, LaValley MP, Harvey WF, et al. Effect of intra-articular triamcinolone vs saline on knee cartilage volume and pain in patients with knee osteoarthritis: a randomized clinical trial. JAMA. 2017;317(19):1967-75. doi:10.1001/jama.2017.5283
- Bioventus LLC. Quantity of DUROLANE patients treated. Data on file, RPT-001056.
- Osteoarthritis Research Society International. What is osteoarthritis? Accessed July 28, 2020. www.oarsi.org/what-osteoarthritis
- Arthritis Society Canada. What is arthritis. Accessed July 28, 2020. https://arthritis.ca/about-arthritis/what-is-arthritis
- Arthritis Society Canada. Osteoarthritis. Accessed September 2017. https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/osteoarthritis
- Arthritis Foundation. Osteoarthritis. Accessed July 28, 2020. https://www.arthritis.org/diseases/osteoarthritis
- Takahashi K, Hashimoto S, Kubo T, Hirasawa Y, Lotz M, Amiel D. Effect of hyaluronan on chondrocyte apoptosis and nitric oxide production in experimentally induced osteoarthritis. J Rheumatol. 2000;27(7):1713-20.
- Mayo Clinic. Exercise helps ease arthritis pain and stiffness. Last updated September 21, 2023. www.mayoclinic.org/diseases-conditions/arthritis/in-depth/arthritis/art-20047971
- Government of Canada. Health Canada clarifies position on platelet rich plasma. Accessed July 16, 2020. Last updated August 26, 2019. https://recalls-rappels.canada.ca/en/alert-recall/health-canada-clarifies-position-platelet-rich-plasma-treatments
- Altman RD, Manjoo A, Fierlinger A, Niazi F, Nicholls M. The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review. BMC Musculoskelet Disord. 2015;16:321. doi:10.1186/s12891-015-0775-z
- Altman RD, Fredericson M, Bhattacharyya SK, et al. Association between hyaluronic acid injections and time-to-total knee replacement surgery. J Knee Surg. 2016;29(7):564-70. doi:10.1055/s-0035-1568992
- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-58. doi:10.4161/derm.21923
- Balazs EA, Denlinger JL. Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol Suppl. 1993;39:3-9.
- Lindqvist U, Tolmachev V, Kairemo K, Aström G, Jonsson E, Lundqvist H. Elimination of stabilised hyaluronan from the knee joint in healthy men. Clin Pharmacokinet. 2002;41(8):603-13. doi:10.2165/00003088-200241080-00004
- Bioventus LLC. DUROLANE 2M patients treated. Bioventus data on file, RPT-001056.
- Zhang H, Zhang K, Zhang X, et al. Comparison of two hyaluronic acid formulations for safety and efficacy (CHASE) study in knee osteoarthritis: a multicenter, randomized, double-blind, 26-week non-inferiority trial comparing Durolane to Artz. Arthritis Res Ther. 2015;17(1):51. doi:10.1186/s13075-015-0557-x
- Edsman K, Hjelm R, Lärkner H, et al. Intra-articular duration of Durolane™ after single injection into the rabbit knee. Cartilage. 2011;2(4)384-8. doi:10.1177/1947603511400184
- Bioventus LLC. Galderma: molecular weight of DUROLANE. Data on file, RPT-000834.
- Larsen NE, Dursema HD, Pollak CT, Skrabut EM. Clearance kinetics of a hylan-based viscosupplement after intra-articular and intravenous administration in animal models. J Biomed Mater Res B Appl Biomater. 2012;100(2):457-62. doi:10.1002/jbm.b.31971
- Brown TJ, Laurent UB, Fraser JR. Turnover of hyaluronan in synovial joints: elimination of labelled hyaluronan from the knee joint of the rabbit. Exp Physiol. 1991;76(1):125-34. doi:10.1113/expphysiol.1991.sp003474
- DUROLANE [package insert]. Durham, NC: Bioventus LLC; 2019.
- Arthritis Foundation. What is osteoarthritis? Accessed February 9, 2019.
- Mackowiak J, Jones J, Dasa V. A comparison of 4-year total medical care costs, adverse outcomes, and opioid/prescription analgesic use for 3 knee osteoarthritis pain treatments: Intra-articular hyaluronic acid, intra-articular corticosteroids, and knee arthroplasty. Semin Arthritis Rheum. 2020;50(6):1525-34. doi:10.1016/j.semarthrit.2020.01.003
- Cleveland Clinic. Osteoarthritis. Last updated October 2, 2023. Accessed September 3, 2021. https://my.clevelandclinic.org/health/diseases/5599-osteoarthritis
- Arthroscopy Association of Canada, Kopka M, Sheehan B, et al. Arthroscopy Association of Canada position statement on intra-articular injections for knee osteoarthritis. Orthop J Sports Med. 2019;7(7):2325967119860110. doi:10.1177/2325967119860110
- Zeng C, Lane NE, Hunter DJ, et al. Intra-articular corticosteroids and the risk of knee osteoarthritis progression: results from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2019;27(6):855-62. doi:10.1016/j.joca.2019.01.007
- Edsman K, Melin H, Näsström J. A study of the ability of Durolane™ to withstand degradation by free radicals while maintaining its viscoelastic properties. Poster presented at: 55th Annual meeting of the Orthopaedic Research Society; February 22-25, 2009; Las Vegas, NV. Poster 1149.
- Maheu E, Bannuru RR, Herrero-Beaumont G, Allali F, Bard H, Migliore A. Why we should definitely include intra-articular hyaluronic acid as a therapeutic option in the management of knee osteoarthritis: results of an extensive critical literature review. Semin Arthritis Rheum. 2019;48(4):563-72. doi:10.1016/j.semarthrit.2018.06.002
- McIntyre L, Beach W, Bhattacharyya S, et al. Impact of hyaluronic acid injections on utilization of pain management medications. Am J Pharm Benefits. 2017;9(6):195-9.